Susceptibility to varicella in childbearing age women, Central Italy: Is there a need for vaccinating this population group?

Valeria Alfonsi, Emanuele Montomoli, Ilaria Manini, Isabella Alberini, Chiara Gentile, Maria Cristina Rota, Marta Luisa Ciofi degli Atti

Research output: Contribution to journalArticle

Abstract

We conducted a cross-sectional seroprevalence study of varicella-zoster virus (VZV) antibodies in childbearing age women aged 17-42 years. Sera were collected in Central Italy in years 2001-2002 and were tested by a commercial VZV IgG enzyme immunoassay. Overall VZV seroprevalence was 80.9% and it showed a significant increase by age, confirming a considerable circulation of VZV also in the older age groups not commonly considered at high risk. This study further supports the importance of vaccinating susceptible adolescents and women of childbearing age in order to reduce both maternal and foetal complications associated with varicella in pregnancy.

Original languageEnglish
Pages (from-to)6086-6088
Number of pages3
JournalVaccine
Volume25
Issue number32
DOIs
Publication statusPublished - Aug 10 2007

Keywords

  • Childbearing-age women
  • Seroepidemiology
  • Varicella

ASJC Scopus subject areas

  • Immunology
  • Microbiology
  • Virology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)

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