Sustained improvement in left ventricular function after bone marrow-derived cell therapy in patients with acute ST elevation myocardial infarction: A 5-year follow-up from the stem cell transplantation in ischaemic myocardium study

Tiziano Moccetti, Daniel Sürder, Catherine Klersy, Giuseppe Vassalli, Carmen Crljenica, Maria Grazia Rossi, Elena Pasotti, Gianni Soldati

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Intracoronary injection of autologous bone marrow-derived mononucleated cells (BM-MNC) may improve LV function shortly after acute ST elevation myocardial infarction (STEMI), but little is known about the long-term durability of the treatment effect. METHODS: In a single-centre trial a total of 60 patients with acute anterior STEMI, successful reperfusion therapy and a left ventricular ejection fraction (LVEF) of

Original languageEnglish
Article numberw13632
JournalSwiss Medical Weekly
Volume142
Issue numberJULY
DOIs
Publication statusPublished - Jul 2012

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Keywords

  • Bone marrow
  • Left ventricular function
  • Myocardial infarction
  • Progenitor cells
  • Remodelling
  • Stem cells

ASJC Scopus subject areas

  • Medicine(all)

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