Swallowing disturbances in Parkinson's disease: A multivariate analysis of contributing factors

Emanuele Cereda, Roberto Cilia, Catherine Klersy, Margherita Canesi, Anna Lena Zecchinelli, Claudio Bruno Mariani, Silvana Tesei, Giorgio Sacilotto, Nicoletta Meucci, Michela Zini, Ioannis Ugo Isaias, Erica Cassani, Stefano Goldwurm, Michela Barichella, Gianni Pezzoli

Research output: Contribution to journalArticlepeer-review


Swallowing disturbances are an important issue in Parkinson's disease (PD) as several studies have shown that they are associated with increased risk of aspiration pneumonia and mortality. Information about factors related to swallowing disturbances, such as disease duration, age at assessment and concomitant dementia, is limited and would be useful for their management. Methods: All consecutive PD out-patients evaluated at a movement disorders clinic over a 7-year period (2007-2014), were included in the present retrospective study. Presence of symptomatic swallowing disturbances was assessed using the specific item of the Non Motor Symptom Questionnaire. Results: In the whole PD population (N=6462), prevalence of symptomatic swallowing disturbances was 11.7% (95%CI, 10.9-12.5). Multivariable logistic regression analysis (adjusted for education) disclosed a significant interaction between disease duration and gender (P=0.009). In both gender strata, swallowing disturbances were significantly associated with longer disease duration and dementia (P

Original languageEnglish
Pages (from-to)1382-1387
Number of pages6
JournalParkinsonism and Related Disorders
Issue number12
Publication statusPublished - Dec 1 2014


  • Dementia
  • Disease duration
  • Dysphagia
  • Parkinson's disease
  • Swallowing disturbances

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Clinical Neurology
  • Neurology


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