TY - JOUR
T1 - Swallowing dysfunction in head and neck cancer patients treated by radiotherapy
T2 - Review and recommendations of the supportive task group of the Italian Association of Radiation Oncology
AU - Russi, Elvio G.
AU - Corvò, Renzo
AU - Merlotti, Anna
AU - Alterio, Daniela
AU - Franco, Pierfrancesco
AU - Pergolizzi, Stefano
AU - De Sanctis, Vitaliana
AU - Ruo Redda, Maria Grazia
AU - Ricardi, Umberto
AU - Paiar, Fabiola
AU - Bonomo, Pierluigi
AU - Merlano, Marco C.
AU - Zurlo, Valeria
AU - Chiesa, Fausto
AU - Sanguineti, Giuseppe
AU - Bernier, Jacques
PY - 2012/12
Y1 - 2012/12
N2 - Purpose: Dysphagia is a debilitating complication in head and neck cancer patients (HNCPs) that may cause a high mortality rate for aspiration pneumonia. The aims of this paper were to summarize the normal swallowing mechanism focusing on its anatomo-physiology, to review the relevant literature in order to identify the main causes of dysphagia in HNCPs and to develop recommendations to be adopted for radiation oncology patients. The chemotherapy and surgery considerations on this topic were reported in recommendations only when they were supposed to increase the adverse effects of radiotherapy on dysphagia. Materials and methods: The review of literature was focused on studies reporting dysphagia as a pre-treatment evaluation and as cancer and cancer therapy related side-effects, respectively. Relevant literature through the primary literature search and by articles identified in references was considered. The members of the group discussed the results and elaborated recommendations according to the Oxford CRBM levels of evidence and recommendations. The recommendations were revised by external Radiation Oncology, Ear Nose and Throat (ENT), Medical Oncology and Speech Language Pathology (SLP) experts. Results: Recommendations on pre-treatment assessment and on patients submitted to radiotherapy were given. The effects of concurrent therapies (i.e. surgery or chemotherapy) were taken into account. Conclusions: In HNCPs treatment, disease control has to be considered in tandem with functional impact on swallowing function. SLPs should be included in a multidisciplinary approach to head and neck cancer.
AB - Purpose: Dysphagia is a debilitating complication in head and neck cancer patients (HNCPs) that may cause a high mortality rate for aspiration pneumonia. The aims of this paper were to summarize the normal swallowing mechanism focusing on its anatomo-physiology, to review the relevant literature in order to identify the main causes of dysphagia in HNCPs and to develop recommendations to be adopted for radiation oncology patients. The chemotherapy and surgery considerations on this topic were reported in recommendations only when they were supposed to increase the adverse effects of radiotherapy on dysphagia. Materials and methods: The review of literature was focused on studies reporting dysphagia as a pre-treatment evaluation and as cancer and cancer therapy related side-effects, respectively. Relevant literature through the primary literature search and by articles identified in references was considered. The members of the group discussed the results and elaborated recommendations according to the Oxford CRBM levels of evidence and recommendations. The recommendations were revised by external Radiation Oncology, Ear Nose and Throat (ENT), Medical Oncology and Speech Language Pathology (SLP) experts. Results: Recommendations on pre-treatment assessment and on patients submitted to radiotherapy were given. The effects of concurrent therapies (i.e. surgery or chemotherapy) were taken into account. Conclusions: In HNCPs treatment, disease control has to be considered in tandem with functional impact on swallowing function. SLPs should be included in a multidisciplinary approach to head and neck cancer.
KW - Aspiration
KW - Chemoradiation
KW - Dysphagia
KW - Head and neck cancer
KW - Radiation oncology
KW - Swallowing dysfunction
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U2 - 10.1016/j.ctrv.2012.04.002
DO - 10.1016/j.ctrv.2012.04.002
M3 - Article
C2 - 22542950
AN - SCOPUS:84867138628
VL - 38
SP - 1033
EP - 1049
JO - Cancer Treatment Reviews
JF - Cancer Treatment Reviews
SN - 0305-7372
IS - 8
ER -