SWI/SNF: The crossroads where extracellular signaling pathways meet chromatin

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The coordinated expression of the genome in response to extracellular cues is ensured by enzymatic cascades signaling to the nucleus. These pathways generate chromatin modifications at specific loci controlling the transcription of signal-dependent and tissue-specific genes. The SWI/SNF chromatin remodeling complex offers the ideal surface for integrating these signals in the execution of diverse or even opposite biological programs.

Original languageEnglish
Pages (from-to)309-314
Number of pages6
JournalJournal of Cellular Physiology
Issue number2
Publication statusPublished - May 2006

ASJC Scopus subject areas

  • Cell Biology
  • Clinical Biochemistry
  • Physiology


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