Abstract
After interruption of highly active antiretroviral therapy, 15 out of 53 patients with the X4 HIV strain had a significantly larger decrease in CD4 + T cell count (P = 0.001) and shorter length of treatment interruption (P = 0.02) than patients with the R5 strain. At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain.
| Original language | English |
|---|---|
| Pages (from-to) | 2586-2588 |
| Number of pages | 3 |
| Journal | Journal of Clinical Microbiology |
| Volume | 48 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2010 |
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ASJC Scopus subject areas
- Microbiology (medical)
- Medicine(all)
Cite this
Switching of inferred tropism caused by HIV during interruption of antiretroviral therapy. / Sarmati, L.; Parisi, S. G.; Andreoni, C.; Nicastri, E.; Buonomini, A. R.; Boldrin, C.; Dori, L.; Montano, M.; Tommasi, C.; Andreis, S.; Vullo, V.; Palù, G.; Andreoni, M.
In: Journal of Clinical Microbiology, Vol. 48, No. 7, 2010, p. 2586-2588.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Switching of inferred tropism caused by HIV during interruption of antiretroviral therapy
AU - Sarmati, L.
AU - Parisi, S. G.
AU - Andreoni, C.
AU - Nicastri, E.
AU - Buonomini, A. R.
AU - Boldrin, C.
AU - Dori, L.
AU - Montano, M.
AU - Tommasi, C.
AU - Andreis, S.
AU - Vullo, V.
AU - Palù, G.
AU - Andreoni, M.
PY - 2010
Y1 - 2010
N2 - After interruption of highly active antiretroviral therapy, 15 out of 53 patients with the X4 HIV strain had a significantly larger decrease in CD4 + T cell count (P = 0.001) and shorter length of treatment interruption (P = 0.02) than patients with the R5 strain. At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain.
AB - After interruption of highly active antiretroviral therapy, 15 out of 53 patients with the X4 HIV strain had a significantly larger decrease in CD4 + T cell count (P = 0.001) and shorter length of treatment interruption (P = 0.02) than patients with the R5 strain. At treatment resumption, HIV inferred tropism switched from the X4 strain to the R5 variant in 9 patients (60%). These patients had a prolonged length of treatment interruption compared to that of those who still carried the X4 strain.
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UR - http://www.scopus.com/inward/citedby.url?scp=77954444321&partnerID=8YFLogxK
U2 - 10.1128/JCM.02125-09
DO - 10.1128/JCM.02125-09
M3 - Article
C2 - 20484604
AN - SCOPUS:77954444321
VL - 48
SP - 2586
EP - 2588
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 7
ER -