Sympathetic predominance in essential hypertension: A study employing spectral analysis of heart rate variability

Stefano Guzzetti, Emanuela Piccaluga 1, Rodolfo Casati 1, Sergio Cerutti, Federico Lombardi 1, Massimo Pagani, Alberto Malliani 1

Research output: Contribution to journalArticlepeer-review

Abstract

In this study on 91 subjects we tested the hypothesis of an enhanced sympathetic activity in uncomplicated essential hypertension employing spectral analysis of heart rate variability. With this technique the tonic sympathetic and vagal activities and their changes are respectively assessed by the power of ~0.1 Hz (low frequency, LF) and ~0.25 Hz (respiratory linked, high frequency, HF) components of the spectrum of the beat by beat variability of RR interval. When comparing the 40 subjects with diastolic blood pressure consistently >95 mmHg (hypertensives, Ht), with 35 age-matched controls (diastolic arterial pressure

Original languageEnglish
Pages (from-to)711-717
Number of pages7
JournalJournal of Hypertension
Volume6
Issue number9
Publication statusPublished - 1988

Keywords

  • Essential hypertension
  • Orthostatic stress
  • RR variability
  • Spectral analysis
  • Sympathetic activity
  • Vagal activity

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Internal Medicine
  • Endocrinology

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