Sympathoadrenergic and metabolic factors are involved in ambulatory blood pressure rise in childhood obesity

L. Gilardini, G. Parati, A. Sartorio, G. Mazzilli, B. Pontiggia, C. Invitti

Research output: Contribution to journalArticle

Abstract

We investigated in a young Italian obese population, the relationship between ambulatory BP (ABP) and several pathophysiological factors linking obesity to hypertension. A total of 89 obese children and adolescents underwent a 24-h ambulatory BP monitoring (ABPM) and an oral glucose tolerance test. The circulating levels of insulin, lipids, uric acid, C-reactive protein, interleukin-6, renin and aldosterone and the 24-h urinary levels of epinephrine, norepinephrine and albumin excretion rate were measured. Nine percent of subjects had daytime sustained hypertension (SH), 26% night-time hypertension and 11% a non-dipping pattern. SH subjects compared to those with sustained normotension (SN) were more obese (P

Original languageEnglish
Pages (from-to)75-82
Number of pages8
JournalJournal of Human Hypertension
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 2008

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ASJC Scopus subject areas

  • Internal Medicine

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