TY - JOUR
T1 - Sympathoadrenergic and metabolic factors are involved in ambulatory blood pressure rise in childhood obesity
AU - Gilardini, L.
AU - Parati, G.
AU - Sartorio, A.
AU - Mazzilli, G.
AU - Pontiggia, B.
AU - Invitti, C.
PY - 2008/2
Y1 - 2008/2
N2 - We investigated in a young Italian obese population, the relationship between ambulatory BP (ABP) and several pathophysiological factors linking obesity to hypertension. A total of 89 obese children and adolescents underwent a 24-h ambulatory BP monitoring (ABPM) and an oral glucose tolerance test. The circulating levels of insulin, lipids, uric acid, C-reactive protein, interleukin-6, renin and aldosterone and the 24-h urinary levels of epinephrine, norepinephrine and albumin excretion rate were measured. Nine percent of subjects had daytime sustained hypertension (SH), 26% night-time hypertension and 11% a non-dipping pattern. SH subjects compared to those with sustained normotension (SN) were more obese (P
AB - We investigated in a young Italian obese population, the relationship between ambulatory BP (ABP) and several pathophysiological factors linking obesity to hypertension. A total of 89 obese children and adolescents underwent a 24-h ambulatory BP monitoring (ABPM) and an oral glucose tolerance test. The circulating levels of insulin, lipids, uric acid, C-reactive protein, interleukin-6, renin and aldosterone and the 24-h urinary levels of epinephrine, norepinephrine and albumin excretion rate were measured. Nine percent of subjects had daytime sustained hypertension (SH), 26% night-time hypertension and 11% a non-dipping pattern. SH subjects compared to those with sustained normotension (SN) were more obese (P
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U2 - 10.1038/sj.jhh.1002288
DO - 10.1038/sj.jhh.1002288
M3 - Article
C2 - 17882228
AN - SCOPUS:38349185617
VL - 22
SP - 75
EP - 82
JO - Journal of Human Hypertension
JF - Journal of Human Hypertension
SN - 0950-9240
IS - 2
ER -