TY - JOUR
T1 - Symptomatic cerebral cavernomas in pregnancy
T2 - A series of 6 cases and review of the literature
AU - Simonazzi, Giuliana
AU - Curti, Alessandra
AU - Rapacchia, Giuseppina
AU - Gabrielli, Sandro
AU - Pilu, Gianluigi
AU - Rizzo, Nicola
AU - Pozzati, Eugenio
PY - 2014/2
Y1 - 2014/2
N2 - Objective: To present our experience of symptomatic cerebral cavernous malformations (CCMs) in pregnancy and to review the literature on the topic. Methods: We retrospectively collected a case series of symptomatic CCMs during pregnancy or the puerperium. A literature search was performed to identify all similar reports. Results: We collected 16 cases of symptomatic CCMs. Haemorrhage occurred in 10 patients. Two patients opted for termination of pregnancy. Delivery occurred preterm in four cases, in only one case due to neurological symptoms at 30 weeks' gestation. Caesarean section was performed in 9 cases; concern over CCM was the indication for delivery in eight of these cases. Four out of 16 patients underwent neurosurgery, three during pregnancy. Conclusion: Symptomatic CCMs seldom require neurosurgery either during or after pregnancy and are not associated with preterm delivery.
AB - Objective: To present our experience of symptomatic cerebral cavernous malformations (CCMs) in pregnancy and to review the literature on the topic. Methods: We retrospectively collected a case series of symptomatic CCMs during pregnancy or the puerperium. A literature search was performed to identify all similar reports. Results: We collected 16 cases of symptomatic CCMs. Haemorrhage occurred in 10 patients. Two patients opted for termination of pregnancy. Delivery occurred preterm in four cases, in only one case due to neurological symptoms at 30 weeks' gestation. Caesarean section was performed in 9 cases; concern over CCM was the indication for delivery in eight of these cases. Four out of 16 patients underwent neurosurgery, three during pregnancy. Conclusion: Symptomatic CCMs seldom require neurosurgery either during or after pregnancy and are not associated with preterm delivery.
KW - Cerebral cavernous malformations
KW - Pregnancy outcome
KW - Symptoms
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U2 - 10.3109/14767058.2013.809417
DO - 10.3109/14767058.2013.809417
M3 - Article
C2 - 23718734
AN - SCOPUS:84891955027
VL - 27
SP - 261
EP - 264
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
SN - 1476-7058
IS - 3
ER -