Symptomatic treatment of benign prostatic obstruction with Nicergoline: A placebo controlled clinical study and urodynamic evaluation

F. Ronchi, A. Margonato, R. Ceccardi, P. Rigatti, B. M. Rossini

Research output: Contribution to journalArticlepeer-review

Abstract

A double-blind crossover study of the alphablocker Nicergoline was carried out in sixteen patients affected by benign prostatic bladder outflow obstruction. The "irritative" symptoms of prostatic hypertrophy, including nocturnal frequency and dysuria, were improved after Nicergoline significantly more than after placebo. In 10 further patients with prostatic hypertrophy, peak and mean flow rates increased by 50% and 77% respectively after the acute administration of Nicergoline. No side effects were detected. In conclusion Nicergoline seems to be active and well tolerated in the treatment of benign prostatic obstruction.

Original languageEnglish
Pages (from-to)131-134
Number of pages4
JournalUrological Research
Volume10
Issue number3
DOIs
Publication statusPublished - Aug 1982

Keywords

  • Benign prostatic obstruction
  • Nicergoline
  • Urodynamic evaluation

ASJC Scopus subject areas

  • Urology

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