Synchronous adenocarcinoma and carcinoid tumor of the terminal ileum in a Crohn's disease patient

Ugo Cioffi, Matilde De Simone, Stefano Ferrero, Michele M. Ciulla, Alessandro Lemos, Ettore Contessini Avesani

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Background: Several malignancies have been described in association with inflammatory bowel diseases, the most common being adenocarcinoma. Carcinoid tumor and Crohn disease has also been previously reported, however the coexistence of both neoplasms is quite rare and the clinical diagnosis is very difficult. Here we report what we believe to be the fourth case of a mixed adenocarcinoid tumor coexisting with Crohn's disease. Case report: The patient presented with clinical and radiological features of intestinal obstruction. Laparotomy showed a stricturing lesion in the last 6 cm of the terminal ileum with proximal dilation. Only the histology of the resected surgical specimen proved the presence of a mixed adenocarcinoid tumor involving the terminal ileum. Conclusion: Carcinoid tumor should be suspected in elderly patients with Crohn's disease presenting with intestinal obstruction and laparotomy should be considered to exclude malignancy.

Original languageEnglish
Article number157
JournalBMC Cancer
Publication statusPublished - Dec 8 2005

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Genetics


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