A 28-year-old man presented a complete syndrome of mineralocorticoid and glucocorticoid excess due to the long-term use of a nasal spray containing 9 alpha-fluoroprednisolone, a synthetic steroid which was found to have potent glucocorticoid and mineralocorticoid activity. After the withdrawal of the intranasal application of this steroid the clinical, biochemical and hormonal abnormalities gradually diseappeared. No previous report has been found of such a syndrome resulting from chronic intake of 9 alpha-fluoroprednisolone by the nasal route.
|Number of pages||4|
|Journal||International Journal of Clinical Pharmacology Research|
|Publication status||Published - 1981|
ASJC Scopus subject areas
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)