Six epileptic patients (4 M, 2 F 18 to 63 yrs of age), with partial complex seizures refractory to standard anticonvulsivant therapy showed a remarkable benefit by taking a comedication of valproic acid and lamotrigine. A pharmacodynamic interaction between the two drugs is suggested.
|Translated title of the contribution||Synergistic effect of Lamotrigine-Valproate comedication in patients with refractory epilepsy|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Clinical Neurology