Synergistic influences of sensory and central stimuli on non-voluntary rhythmic arm movements

I. A. Solopova, D. S. Zhvansky, V. A. Selionov, Y. Ivanenko

Research output: Contribution to journalArticle

Abstract

In recent years, neuromodulation of the cervical spinal circuitry has become an area of interest for investigating rhythmogenesis of the human spinal cord and interaction between cervical and lumbosacral circuitries, given the involvement of rhythmic arm muscle activity in many locomotor tasks. We have previously shown that arm muscle vibrostimulation can elicit non-voluntary upper limb oscillations in unloading body conditions. Here we investigated the excitability of the cervical spinal circuitry by applying different peripheral and central stimuli in healthy humans. The rationale for applying combined stimuli is that the efficiency of only one stimulus is generally limited. We found that low-intensity electrical stimulation of the superficial arm median nerve can evoke rhythmic arm movements. Furthermore, the movements were enhanced by additional peripheral stimuli (e.g., arm muscle vibration, head turns or passive rhythmic leg movements). Finally, low-frequency transcranial magnetic stimulation of the motor cortex significantly facilitated rhythmogenesis. The findings are discussed in the general framework of a brain-spinal interface for developing adaptive central pattern generator-modulating therapies.

Original languageEnglish
Pages (from-to)230-239
Number of pages10
JournalHuman Movement Science
Volume64
DOIs
Publication statusPublished - Apr 1 2019

Fingerprint

Arm
Muscles
Central Pattern Generators
Transcranial Magnetic Stimulation
Median Nerve
Motor Cortex
Vibration
Upper Extremity
Electric Stimulation
Leg
Spinal Cord
Head
Brain
Therapeutics

Keywords

  • Arm-leg interaction in humans
  • Central pattern generator
  • Cervical spinal cord
  • Sensory stimulation
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Experimental and Cognitive Psychology

Cite this

Synergistic influences of sensory and central stimuli on non-voluntary rhythmic arm movements. / Solopova, I. A.; Zhvansky, D. S.; Selionov, V. A.; Ivanenko, Y.

In: Human Movement Science, Vol. 64, 01.04.2019, p. 230-239.

Research output: Contribution to journalArticle

Solopova, I. A. ; Zhvansky, D. S. ; Selionov, V. A. ; Ivanenko, Y. / Synergistic influences of sensory and central stimuli on non-voluntary rhythmic arm movements. In: Human Movement Science. 2019 ; Vol. 64. pp. 230-239.
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