Synthesis and antiaggregant properties of new analogues of polyunsaturated fatty acid metabolites with naphthalene or quinoline cores

Ali Hachem, Yves L. Floc'h, René Grée, Chiara Cerletti, Yves Rolland, Serge Simonet, Tony Verbeuren

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

New bicyclic analogues of polyunsaturated fatty acid metabolites have been prepared using short and efficient routes. Preliminary studies of their activity as inhibitors of platelet aggregation are reported.

Original languageEnglish
Pages (from-to)5221-5223
Number of pages3
JournalTetrahedron Letters
Volume43
Issue number30
DOIs
Publication statusPublished - Jul 22 2002

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Platelet Aggregation Inhibitors
Metabolites
Unsaturated Fatty Acids
naphthalene
quinoline

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis and antiaggregant properties of new analogues of polyunsaturated fatty acid metabolites with naphthalene or quinoline cores. / Hachem, Ali; Floc'h, Yves L.; Grée, René; Cerletti, Chiara; Rolland, Yves; Simonet, Serge; Verbeuren, Tony.

In: Tetrahedron Letters, Vol. 43, No. 30, 22.07.2002, p. 5221-5223.

Research output: Contribution to journalArticle

Hachem, Ali ; Floc'h, Yves L. ; Grée, René ; Cerletti, Chiara ; Rolland, Yves ; Simonet, Serge ; Verbeuren, Tony. / Synthesis and antiaggregant properties of new analogues of polyunsaturated fatty acid metabolites with naphthalene or quinoline cores. In: Tetrahedron Letters. 2002 ; Vol. 43, No. 30. pp. 5221-5223.
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