Synthesis and antiviral activity of dihydroxycyclohexyl pyrimidine and purine carbocyclic nucleosides

F. Calvani, M. Macchia, A. Rossello, M. R. Gismondo, L. Drago, M. C. Fassina, M. Cisternino, P. Domiano

Research output: Contribution to journalArticle

Abstract

Some novel dihydroxycyclohexyl pyrimidine and purine carbocyclic nucleosides were prepared and tested for inhibitory activity against Cytomegalovirus and Herpes virus- 1 and -2.

Original languageEnglish
Pages (from-to)2567-2572
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume5
Issue number21
DOIs
Publication statusPublished - Nov 2 1995

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ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Molecular Biology
  • Molecular Medicine
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Calvani, F., Macchia, M., Rossello, A., Gismondo, M. R., Drago, L., Fassina, M. C., Cisternino, M., & Domiano, P. (1995). Synthesis and antiviral activity of dihydroxycyclohexyl pyrimidine and purine carbocyclic nucleosides. Bioorganic and Medicinal Chemistry Letters, 5(21), 2567-2572. https://doi.org/10.1016/0960-894X(95)00439-Z