Synthesis and interactions of cytoplasmic membranes in the pancreatic exocrine cells

Jacopo Meldolesi, Dario Cova

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis and interactions of cytoplasmic membranes involved in the intracellular transport of secretory proteins have been investigated in a system of guinea pig pancreas slices pulse labeled in vitro with 14C-L-leucine. It is suggested that the membranes of the rough endoplasmic reticulum and Golgi complex were synthetized independently of each other while the membranes of zymogen granules derive from preexisting structures, probably membranes of Golgi origin.

Original languageEnglish
Pages (from-to)139-143
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume44
Issue number1
DOIs
Publication statusPublished - Jul 2 1971

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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