Synthesis of a new series of 8-substituted-2,8-diazaspiro[4.5]decan-3- ones

G. Cignarella, S. Villa, D. Barlocco

Research output: Contribution to journalArticlepeer-review

Abstract

A new series of 8-substituted-2,8-diazaspiro[4.5]decan-3-ones has been synthesized and tested in in vitro and in vivo assays predictive for cholinergic activity, in comparison with the muscarinic agent RS-86. Preliminary pharmacological data indicate that the compounds are devoid of significant cholinergic properties.

Original languageEnglish
Pages (from-to)1357-1359
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume30
Issue number5
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Organic Chemistry

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