Abstract
A new series of 8-substituted-2,8-diazaspiro[4.5]decan-3-ones has been synthesized and tested in in vitro and in vivo assays predictive for cholinergic activity, in comparison with the muscarinic agent RS-86. Preliminary pharmacological data indicate that the compounds are devoid of significant cholinergic properties.
| Original language | English |
|---|---|
| Pages (from-to) | 1357-1359 |
| Number of pages | 3 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 30 |
| Issue number | 5 |
| Publication status | Published - 1993 |
ASJC Scopus subject areas
- Organic Chemistry