Synthesis of dihydrolysergol analogues

S. Mantegani, G. Traquandi, M. Varasi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

As a part of a search for novel biological active ergoline derivatives, the indole ring present in the ergoline skeleton (indole[4,3-f,g]quinoline) was converted into different heterocyclic ring systems such as quinazoline 2, benzofurane 3 and benzoxazole 4. Due to the paramount importance of chirality to attain biological activity, natural dihydrolysergic acid 1 was chosen as starting material and a synthetic pathway conservative in term of chirality was followed.

Original languageEnglish
Pages (from-to)759-763
Number of pages5
JournalJournal of Heterocyclic Chemistry
Volume38
Issue number3
Publication statusPublished - 2001

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Ergolines
Chirality
Benzoxazoles
Quinazolines
Bioactivity
Derivatives
Acids
indole

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Mantegani, S., Traquandi, G., & Varasi, M. (2001). Synthesis of dihydrolysergol analogues. Journal of Heterocyclic Chemistry, 38(3), 759-763.

Synthesis of dihydrolysergol analogues. / Mantegani, S.; Traquandi, G.; Varasi, M.

In: Journal of Heterocyclic Chemistry, Vol. 38, No. 3, 2001, p. 759-763.

Research output: Contribution to journalArticle

Mantegani, S, Traquandi, G & Varasi, M 2001, 'Synthesis of dihydrolysergol analogues', Journal of Heterocyclic Chemistry, vol. 38, no. 3, pp. 759-763.
Mantegani S, Traquandi G, Varasi M. Synthesis of dihydrolysergol analogues. Journal of Heterocyclic Chemistry. 2001;38(3):759-763.
Mantegani, S. ; Traquandi, G. ; Varasi, M. / Synthesis of dihydrolysergol analogues. In: Journal of Heterocyclic Chemistry. 2001 ; Vol. 38, No. 3. pp. 759-763.
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