Synthesis of dihydrolysergol analogues

S. Mantegani, G. Traquandi, M. Varasi

Research output: Contribution to journalArticlepeer-review


As a part of a search for novel biological active ergoline derivatives, the indole ring present in the ergoline skeleton (indole[4,3-f,g]quinoline) was converted into different heterocyclic ring systems such as quinazoline 2, benzofurane 3 and benzoxazole 4. Due to the paramount importance of chirality to attain biological activity, natural dihydrolysergic acid 1 was chosen as starting material and a synthetic pathway conservative in term of chirality was followed.

Original languageEnglish
Pages (from-to)759-763
Number of pages5
JournalJournal of Heterocyclic Chemistry
Issue number3
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Organic Chemistry


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