Synthesis of novel neuroexcitatory amino acids derived from kainic acid

Ora Goldberg, Alberto Luini, Vivian I. Teichberg

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis of the novel epimeric amino acids 5a and 7a by oxidation of methyl ketones derived from kainic acid is described. On biological testing both compounds exhibit a strong neuroexcitatory activity.

Original languageEnglish
Pages (from-to)2355-2358
Number of pages4
JournalTetrahedron Letters
Volume21
Issue number24
DOIs
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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