Synthesis of novel neuroexcitatory amino acids derived from kainic acid

Ora Goldberg, Alberto Luini, Vivian I. Teichberg

Research output: Contribution to journalArticle

Abstract

The synthesis of the novel epimeric amino acids 5a and 7a by oxidation of methyl ketones derived from kainic acid is described. On biological testing both compounds exhibit a strong neuroexcitatory activity.

Original languageEnglish
Pages (from-to)2355-2358
Number of pages4
JournalTetrahedron Letters
Volume21
Issue number24
DOIs
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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