Abstract
1,2,3,4-Tetrahydro-6,7-dihydroxy-1-methylisoquinoline-1-carboxylic acid (salsolinol-1-carboxylic acid) has been shown to be a bioprecursor of (R)-salsolinol in humans. We report here a synthesis and the determination of the absolute configurations of both enantiomers of salsolinol-1-carboxylic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 57-59 |
| Number of pages | 3 |
| Journal | European Journal of Medicinal Chemistry |
| Volume | 27 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1992 |
Keywords
- mammalian alkaloids
- R and S enantiomers
- salsolinol-1-carboxylic acid
ASJC Scopus subject areas
- Molecular Medicine
- Organic Chemistry
- Drug Discovery
- Pharmaceutical Science
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Dostert, P., Varasi, M., Torre, A. D., Monti, C., & Rizzo, V. (1992). Synthesis of the R and S enantiomers of 1,2,3,4-tetrahydro-6,7-dihydroxy-1-methylisoquinoline-1-carboxylic acid. European Journal of Medicinal Chemistry, 27(1), 57-59. https://doi.org/10.1016/0223-5234(92)90061-5