Abstract
1,2,3,4-Tetrahydro-6,7-dihydroxy-1-methylisoquinoline-1-carboxylic acid (salsolinol-1-carboxylic acid) has been shown to be a bioprecursor of (R)-salsolinol in humans. We report here a synthesis and the determination of the absolute configurations of both enantiomers of salsolinol-1-carboxylic acid.
Original language | English |
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Pages (from-to) | 57-59 |
Number of pages | 3 |
Journal | European Journal of Medicinal Chemistry |
Volume | 27 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1992 |
Keywords
- mammalian alkaloids
- R and S enantiomers
- salsolinol-1-carboxylic acid
ASJC Scopus subject areas
- Molecular Medicine
- Organic Chemistry
- Drug Discovery
- Pharmaceutical Science