Systematic review of guidelines to identify recommendations for upper limb robotic rehabilitation after stroke

CICERONE Italian Consensus Conference on Robotic in Neurorehabilitation, Giovanni Morone, Angela Palomba, Alex Martino Cinnera, Michela Agostini, Irene Aprile, Chiara Arienti, Matteo Paci, Emanuela Casanova, Dario Marino, Giuseppe Larosa, Federica Bressi, Silvia Sterzi, Marialuisa Gandolfi, Daniele Giansanti, Luca Perrero, Alberto Battistini, Sandra Miccinilli, Serena Filoni, Monica SicariSalvatore Petrozzino, Claudio Marcello Solaro, Stefano Gargano, Paolo Benanti, Paolo Boldrini, Donatella Bonaiuti, Enrico Castelli, Francesco Draicchio, Vincenzo Falabella, Silvia Galeri, Francesca Gimigliano, Mauro Grigioni, Stefano Mazzoleni, Stefano Mazzon, Franco Molteni, Maurizio Petrarca, Alessandro Picelli, Federico Posteraro, Michele Senatore, Giuseppe Turchetti, Sofia Straudi, Ludovica Baluardo, Valentina Boetto, Marco Bravi, Diletta Bruno, Manuela Desilvestri, Lorenzo Lippi, Cristiano Pecchioli, Emanuele F. Russo, Fabio Santacaterina

Research output: Contribution to journalReview articlepeer-review


Introduction: Upper limb motor impairment is one of the most frequent stroke consequences. robot therapy may represent a valid option for upper limb stroke rehabilitation, but there are still gaps between research evidence and their use in clinical practice. the aim of this study was to determine the quality, scope, and consistency of guidelines clinical practice recommendations for upper limb robotic rehabilitation in stroke populations. EVidEncE acQuisition: We searched for guideline recommendations on stroke published between January 1st, 2010 and January 1st, 2020. only the most recent guidelines for writing group were selected. Electronic databases (n.=4), guideline repertories and professional rehabilitation networks (n.=12) were searched. We systematically reviewed and assessed guidelines containing recommendation statements about upper limb robotic rehabilitation for adults with stroke (prospEro registration number: crd42020173386). EVidEncE synthEsis: four independent reviewers used the appraisal of Guidelines for research and Evaluation (aGrEE) ii instrument, and textual syntheses were used to appraise and compare recommendations. from 1324 papers that were screened, eight eligible guidelines were identified from six different regions/countries. Half of the included guidelines focused on stroke management, the other half on stroke rehabilitation. rehabilitation assisted by robotic devices is generally recommended to improve upper limb motor function and strength. the exact characteristics of patients who could benefit from this treatment as well as the correct timing to use it are not known. CONCLUSIONS: This systematic review has identified many opportunities to modernize and otherwise improve stroke patients’ upper limb robotic therapy. rehabilitation assisted by robot or electromechanical devices for stroke needs to be improved in clinical practice guidelines in particular in terms of applicability.

Original languageEnglish
Pages (from-to)238-245
Number of pages8
JournalEuropean Journal of Physical and Rehabilitation Medicine
Issue number2
Publication statusPublished - Apr 2021


  • Guideline
  • Rehabilitation
  • Robotic surgical procedures
  • Stroke
  • Upper extremity

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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