Systematic review: The role of self-expanding plastic stents for benign oesophageal strictures

A. Repici, C. Hassan, P. Sharma, M. Conio, P. Siersema

Research output: Contribution to journalArticlepeer-review


Treatment of refractory or recurrent benign oesophageal strictures is demanding and surgery may be the only available option. The role of self-expanding plastic stents (SEPS) in the treatment of these strictures is still controversial because of the conflicting results of various studies. Aim To analyse with regard to SEPS: technical and clinical success, factors associated with outcome, and safety. Methods Pooled-data analysis of a systematic review of the literature. Clinical success was defined as no need for further endoscopic or surgical treatment after SEPS removal. Results Data of 10 studies with 130 treated patients were included. SEPS insertion was technically successful in 128 of 130 patients (98%, 95% CI = 96-100%). Clinical success was achieved in 68 patients (52%, 95% CI = 44-61%) and this was found to be lower in those with a cervical localization of the stricture (33% vs. 54%; P <0.05). Early (

Original languageEnglish
Pages (from-to)1268-1275
Number of pages8
JournalAlimentary Pharmacology and Therapeutics
Issue number12
Publication statusPublished - Jun 2010

ASJC Scopus subject areas

  • Pharmacology (medical)


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