Systematic ultrasound-guided saturation and template biopsy of the prostate: Indications and advantages of extended sampling

Hendrik Isbarn, Alberto Briganti, Pieter J L De Visschere, Jurgen J. Fütterer, Pirus Ghadjar, Gianluca Giannarini, Piet Ost, Guillaume Ploussard, Prasanna Sooriakumaran, Christian I. Surcel, Inge M. Van Oort, Ofer Yossepowitch, Roderick C N Van Den Bergh

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: Prostate biopsy (PB) is the gold standard for the diagnosis of prostate cancer (PCa). However, the optimal number of biopsy cores remains debatable. We sought to compare contemporary standard (10-12 cores) vs. saturation (≥18 cores) schemes on initial as well as repeat PB. METHODS: A non-systematic review of the literature was performed from 2000 through 2013. Studies of highest evidence (randomized controlled trials, prospective non-randomized studies, and retrospective reports of high quality) comparing standard vs saturation schemes on initial and repeat PB were evaluated. Outcome measures were overall PCa detection rate, detection rate of insignificant PCa, and procedure-associated morbidity. RESULTS: On initial PB, there is growing evidence that a saturation scheme is associated with a higher PCa detection rate compared to a standard one in men with lower PSA levels (40 cc), or lower PSA density values (

Original languageEnglish
Pages (from-to)296-306
Number of pages11
JournalArchivos Espanoles de Urologia
Volume68
Issue number3
Publication statusPublished - Apr 1 2015

Keywords

  • Complications
  • Prostate biopsy
  • Prostate neoplasms
  • Saturation biopsy
  • Significant prostate cancer
  • Template biopsy

ASJC Scopus subject areas

  • Urology

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