Systemic administration of ephedrine induces Fos protein expression in caudate putamen and subthalamic nucleus of rats

Fabio Blandini, Shirley Ann Joseph, Cristina Tassorelli

Research output: Contribution to journalArticlepeer-review

Abstract

Systemic administration of ephedrine, an anti-hypotensive agent with central effects, induced dramatic expression of Fos protein in the caudate putamen (CPu) and subthalamic nucleus (STN) of rats. This may be related to dopaminergic agonist properties that have been attributed to this compound, dopamine receptors being present in both CPu and STN. This finding seems to suggest that central effects of ephedrine might be mediated by changes in basal ganglia outflow.

Original languageEnglish
Pages (from-to)293-296
Number of pages4
JournalFunctional Neurology
Volume12
Issue number5
Publication statusPublished - Sep 1997

Keywords

  • Caudate putamen
  • Ephedrine
  • Fos
  • Subthalamic nucleus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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