Systemic fungemia and hepatic localization of Fusarium Solani in a liver transplanted patient: An emerging fungal agent

Francesca Lodato, Maria Rosa Tamé, Marco Montagnani, Vittorio Sambri, Giovanna Liguori, Francesco Azzaroli, Paolo Costigliola, Gianluca Grazi, Enrico Roda, Giuseppe Mazzella

Research output: Contribution to journalArticle

Abstract

The incidence of invasive fungal infection is increasing especially in the field of transplantation, affecting as many as 50% of bone marrow transplant (BMT) patients with neutropenia and 5-20% of solid-organ transplant (SOT) recipients. Fusarium species are soil saprophytes and plant pathogens. They may cause superficial mycoses or important opportunistic infections in patients with bone marrow suppression and neutropenia, they have been rarely described in solid organ recipients, and up to now there have been no reports of such infection in isolated liver transplanted patients. We describe a case of disseminated Fusarium solani infection with hepatic localization in a liver transplanted patient that resolved with the administration of amphotericin B. Our observation confirms that Fusarium spp. are emerging pathogens that may most frequently affect not only BMT patients and patients with hematological malignancies, but also SOT patients. They may cause both localized and disseminated infection. In conclusion, Fusarium spp. etiology should be considered in the context of infectious diseases following liver transplantation.

Original languageEnglish
Pages (from-to)1711-1714
Number of pages4
JournalLiver Transplantation
Volume12
Issue number11
DOIs
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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    Lodato, F., Tamé, M. R., Montagnani, M., Sambri, V., Liguori, G., Azzaroli, F., Costigliola, P., Grazi, G., Roda, E., & Mazzella, G. (2006). Systemic fungemia and hepatic localization of Fusarium Solani in a liver transplanted patient: An emerging fungal agent. Liver Transplantation, 12(11), 1711-1714. https://doi.org/10.1002/lt.20899