Maladie de Still de l'enfant, évolution conceptuelle et thérapeutique

Translated title of the contribution: Systemic juvenile idiopathic arthritis: New pathogenetic and therapeutic aspects

Research output: Contribution to journalArticlepeer-review

Abstract

Systemic juvenile idiopathic arthritis (sJIA) sets well apart from all the other forms of JIA. Several observations show that sJIA is etiopathogenically different from all the other forms of JIA and has a prominent autoinflammatory component. A major role in particular is played by two proinflammatory cytokines, interleukin-6 and interleukin-1. The specific inhibition of these two cytokines is going to change not only the therapeutic approach to the disease but also, presumably, its long-term prognosis.

Translated title of the contributionSystemic juvenile idiopathic arthritis: New pathogenetic and therapeutic aspects
Original languageFrench
Pages (from-to)3-6
Number of pages4
JournalRevue du Rhumatisme Monographies
Volume79
Issue number1
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Autoinflammatory disease
  • Interleukin-1
  • Interleukin-6

ASJC Scopus subject areas

  • Rheumatology

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