Systemic treatments for brain metastases from breast cancer, non-small cell lung cancer, melanoma and renal cell carcinoma

An overview of the literature

Giuseppe Lombardi, Anna Luisa Di Stefano, Patrizia Farina, Vittorina Zagonel, Emeline Tabouret

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The frequency of metastatic brain tumors has increased over recent years; the primary tumors most involved are breast cancer, lung cancer, melanoma and renal cell carcinoma. While radiation therapy and surgery remain the mainstay treatment in selected patients, new molecular drugs have been developed for brain metastases. Studies so far report interesting results.This review focuses on systemic cytotoxic drugs and, in particular, on new targeted therapies and their clinically relevant activities in brain metastases from solid tumors in adults.

Original languageEnglish
Pages (from-to)2013
Number of pages1
JournalCancer Treatment Reviews
Volume40
Issue number8
DOIs
Publication statusPublished - 2014

Fingerprint

Renal Cell Carcinoma
Non-Small Cell Lung Carcinoma
Melanoma
Lung Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Brain
Brain Neoplasms
Pharmaceutical Preparations
Neoplasms
Radiotherapy
Therapeutics

Keywords

  • Brain metastases
  • Breast cancer
  • Lung cancer
  • Melanoma
  • Renal cell carcinoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Systemic treatments for brain metastases from breast cancer, non-small cell lung cancer, melanoma and renal cell carcinoma : An overview of the literature. / Lombardi, Giuseppe; Di Stefano, Anna Luisa; Farina, Patrizia; Zagonel, Vittorina; Tabouret, Emeline.

In: Cancer Treatment Reviews, Vol. 40, No. 8, 2014, p. 2013.

Research output: Contribution to journalArticle

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