T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers: A longitudinal evaluation

Antonella D Arminio Monforte, Roberto Novati, Massimo Galli, Paola Marchisio, Emilia Massironi, Raffaella Tornaghi, Alberto Saracco, Nicola Principi, Mauro Moroni

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.

Original languageEnglish
Pages (from-to)1141-1144
Number of pages4
JournalAIDS (London, England)
Volume4
Issue number11
Publication statusPublished - Nov 1990

Fingerprint

T-Lymphocyte Subsets
Immunoglobulins
Mothers
HIV
CD4-CD8 Ratio
CD4 Lymphocyte Count
Serum
Parturition
Newborn Infant

Keywords

  • HIV seroreverted infants
  • HIV-infected infants
  • Serum immunoglobulin levels
  • T-lymphocyte subsets

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Monforte, A. D. A., Novati, R., Galli, M., Marchisio, P., Massironi, E., Tornaghi, R., ... Moroni, M. (1990). T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers: A longitudinal evaluation. AIDS (London, England), 4(11), 1141-1144.

T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers : A longitudinal evaluation. / Monforte, Antonella D Arminio; Novati, Roberto; Galli, Massimo; Marchisio, Paola; Massironi, Emilia; Tornaghi, Raffaella; Saracco, Alberto; Principi, Nicola; Moroni, Mauro.

In: AIDS (London, England), Vol. 4, No. 11, 11.1990, p. 1141-1144.

Research output: Contribution to journalArticle

Monforte, ADA, Novati, R, Galli, M, Marchisio, P, Massironi, E, Tornaghi, R, Saracco, A, Principi, N & Moroni, M 1990, 'T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers: A longitudinal evaluation', AIDS (London, England), vol. 4, no. 11, pp. 1141-1144.
Monforte, Antonella D Arminio ; Novati, Roberto ; Galli, Massimo ; Marchisio, Paola ; Massironi, Emilia ; Tornaghi, Raffaella ; Saracco, Alberto ; Principi, Nicola ; Moroni, Mauro. / T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers : A longitudinal evaluation. In: AIDS (London, England). 1990 ; Vol. 4, No. 11. pp. 1141-1144.
@article{17c2e7f08b7844bea5fcdaf5242b2386,
title = "T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers: A longitudinal evaluation",
abstract = "T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.",
keywords = "HIV seroreverted infants, HIV-infected infants, Serum immunoglobulin levels, T-lymphocyte subsets",
author = "Monforte, {Antonella D Arminio} and Roberto Novati and Massimo Galli and Paola Marchisio and Emilia Massironi and Raffaella Tornaghi and Alberto Saracco and Nicola Principi and Mauro Moroni",
year = "1990",
month = "11",
language = "English",
volume = "4",
pages = "1141--1144",
journal = "AIDS",
issn = "0269-9370",
publisher = "NLM (Medline)",
number = "11",

}

TY - JOUR

T1 - T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers

T2 - A longitudinal evaluation

AU - Monforte, Antonella D Arminio

AU - Novati, Roberto

AU - Galli, Massimo

AU - Marchisio, Paola

AU - Massironi, Emilia

AU - Tornaghi, Raffaella

AU - Saracco, Alberto

AU - Principi, Nicola

AU - Moroni, Mauro

PY - 1990/11

Y1 - 1990/11

N2 - T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.

AB - T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.

KW - HIV seroreverted infants

KW - HIV-infected infants

KW - Serum immunoglobulin levels

KW - T-lymphocyte subsets

UR - http://www.scopus.com/inward/record.url?scp=0025647199&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025647199&partnerID=8YFLogxK

M3 - Article

C2 - 2282187

AN - SCOPUS:0025647199

VL - 4

SP - 1141

EP - 1144

JO - AIDS

JF - AIDS

SN - 0269-9370

IS - 11

ER -