T cells cross-link innate and adaptive immunity in mycobacterium tuberculosis infection

Angelo Martino, Serena Meraviglia, Sary El Daker, Francesco Dieli, Federico Martini

Research output: Contribution to journalArticlepeer-review

Abstract

Protective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations on T lymphocytes and their role in tuberculosis immunity.

Original languageEnglish
Article number587315
JournalClinical and Developmental Immunology
Volume2011
DOIs
Publication statusPublished - 2011

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Medicine(all)

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