T lymphocyte subpopulations in Graves' disease: Relationship with clinical conditions

M. Bagnasco, G. W. Canonica, S. Ferrini, P. Biassoni, G. Melioli, O. Ferrini, G. Giordano

Research output: Contribution to journalArticle

Abstract

T lymphocytes were fractionated according to their receptors for IgG (T(G)) or IgM (T(M)) and scored in 37 patients with Graves' disease (17 hyperthyroid and untreated, 10 euthyroid on antithyroid drugs, 10 in long-term remission after radioiodine therapy). T(G) percentages were very low both in untreated and in drug-treated patients. By contrast, normal T(G) levels were observed in patients in long-term remission. These data are consistent with the hypothesis of a defective suppressor cell activity in Graves' disease.

Original languageEnglish
Pages (from-to)213-219
Number of pages7
JournalActa Endocrinologica
Volume102
Issue number2
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Endocrinology

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    Bagnasco, M., Canonica, G. W., Ferrini, S., Biassoni, P., Melioli, G., Ferrini, O., & Giordano, G. (1983). T lymphocyte subpopulations in Graves' disease: Relationship with clinical conditions. Acta Endocrinologica, 102(2), 213-219.