t(21q21q)/r[t(21q21q)] Mosaic in two unrelated patients with mild stigmata of Down's syndrome

B. Dallapiccola, I. Bianco, V. Brinchi, B. Santulli, G. Scarano, A. Sicolo, M. Stabile, V. Ventruto

Research output: Contribution to journalArticle

Abstract

Two cases of t(21q21q)/r[t(21q21q)] mosaic in unrelated infants, 17 and 14 months old respectively are reported. The proportion of cells with the ring chromosome was 45% in the former, 80% in the latter. Both cases had mild manifestations of the Down's syndrome. The origin of this unusual mosaicism as well as the significance of the difference in the proportions of the ring chromosome in the two have been discussed.

Original languageEnglish
Pages (from-to)56-58
Number of pages3
JournalAnnales de Genetique
Volume25
Issue number1
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Genetics

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  • Cite this

    Dallapiccola, B., Bianco, I., Brinchi, V., Santulli, B., Scarano, G., Sicolo, A., Stabile, M., & Ventruto, V. (1982). t(21q21q)/r[t(21q21q)] Mosaic in two unrelated patients with mild stigmata of Down's syndrome. Annales de Genetique, 25(1), 56-58.