Tag-based next generation sequencing: A feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients: Molecular Medicine

M. Dono, G. De Luca, S. Lastraioli, G. Anselmi, M.G. Dal Bello, S. Coco, I. Vanni, F. Grossi, A. Vigani, C. Genova, M. Ferrarini, J.L. Ravetti, S. Zupo

Research output: Contribution to journalArticle

Original languageEnglish
Article number15
JournalMol. Med.
Volume25
Issue number1
DOIs
Publication statusPublished - 2019

Keywords

  • C797S
  • Circulating tumor DNA
  • EGFR TKIs
  • Liquid biopsy
  • Molecular tag
  • Next generation sequencing
  • NSCLC
  • T790M resistance mutation
  • circulating tumor DNA
  • osimertinib
  • protein tyrosine kinase inhibitor
  • epidermal growth factor receptor
  • accuracy
  • adult
  • aged
  • allele
  • Article
  • clinical article
  • cohort analysis
  • controlled study
  • cytology
  • EGFR gene
  • feasibility study
  • female
  • gene mutation
  • genetic variability
  • human
  • human tissue
  • lung biopsy
  • male
  • middle aged
  • next generation sequencing
  • non small cell lung cancer
  • oncogene
  • priority journal
  • real time polymerase chain reaction
  • reliability
  • sensitivity analysis
  • very elderly
  • genetics
  • high throughput sequencing
  • lung tumor
  • mutation
  • procedures
  • Carcinoma, Non-Small-Cell Lung
  • Circulating Tumor DNA
  • ErbB Receptors
  • Female
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Lung Neoplasms
  • Male
  • Mutation

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