Tamoxifene e patologia genitale femminile correlata. Considerazioni generali ed esperienza clinica

Translated title of the contribution: Tamoxifen and female genital diseases. General considerations and clinical experience

N. De Frenza, G. Falco, A. Traversa, M. De Liso, G. Simone, V. Rubini, F. A. Zito

Research output: Contribution to journalArticle

Abstract

Tamoxifen (TAM) is non-steroid triphenilethylene derivative with estrogen agonist-antagonist properties. In oncology it is used the tumoristatic TAM-action. Nowadays, TAM is the elective treatment for post- menopausal patients with breast cancer and positive lymphnodes as well as for pre-menopausal patients with negative nodes and positive estrogen receptors. It's acknowledged the efficiency of TAM in reducing the incidence of contralateral breast cancer up to a prevention use for high risk patients. After an exhaustive bibliographical review, the Authors introduce their study about TAM-induced genital pathology in women with breast cancer. 52 patients were enrolled in this study, treated between 1996-1997 by the Dept. of Gynecology of the Cancer Institute of Bari. The results, according to the literature, demonstrate that it should be better to follow closely the TAM- treated patients, moreover beginning with a preventive check of the > before the TAM-treatment and then to have periodic medical examinations to reduce to a minimum the risk of developing an even serious gynecologic TAM-correlated disease.

Translated title of the contributionTamoxifen and female genital diseases. General considerations and clinical experience
Original languageItalian
Pages (from-to)416-421
Number of pages6
JournalGiornale Italiano di Ostetricia e Ginecologia
Volume20
Issue number9
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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  • Cite this

    De Frenza, N., Falco, G., Traversa, A., De Liso, M., Simone, G., Rubini, V., & Zito, F. A. (1998). Tamoxifene e patologia genitale femminile correlata. Considerazioni generali ed esperienza clinica. Giornale Italiano di Ostetricia e Ginecologia, 20(9), 416-421.