Targeting insulin-like growth factor 1 receptor in sarcomas

Katia Scotlandi, Piero Picci

Research output: Contribution to journalArticlepeer-review

Abstract

Sarcomas are good candidates for the design of a clinical study targeting insulin-like growth factor-I receptor. An attention to schedule with chemotherapy agents and new drugs, measurement of relevant indicators of response and better molecular understanding of the metabolic functions of insulin-like growth factor-I receptor and its functional relationship with insulin receptor are necessary to proceed safely with the design of anti-insulin-like growth factor strategies.

Original languageEnglish
Pages (from-to)419-427
Number of pages9
JournalCurrent Opinion in Oncology
Volume20
Issue number4
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Biomarkers
  • Insulin-like growth factor-I receptor
  • Metabolism
  • Sarcomas
  • Targeted therapies

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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