Tc-99m HMPAO-labeled leukocyte scintigraphy with hybrid SPECT/CT detects perianal fistulas in Crohn disease

Luca Filippi, Livia Biancone, Carmelina Petruzziello, Orazio Schillaci

Research output: Contribution to journalArticle

Abstract

Scintigraphy with Tc-99m HMPAO-labeled leukocytes proved useful to diagnose intestinal lesions in Crohn disease (CD). The hybrid device combining single photon emission tomography (SPECT) and computed tomography (CT) has been reported to improve SPECT diagnostic accuracy matching functional and anatomic information. The authors describe a 30-year-old man with ileorectal anastomosis for CD. In this case, SPECT shows an area of leukocyte accumulation within the pelvis, and SPECT/CT precisely localizes this uptake along a perianal fistulous tract. This image indicates the usefulness of the hybrid SPECT/CT device to assess the site and the extent of CD lesions within the pelvic floor.

Original languageEnglish
Pages (from-to)541-542
Number of pages2
JournalClinical Nuclear Medicine
Volume31
Issue number9
DOIs
Publication statusPublished - Sep 2006

Keywords

  • Crohn disease
  • Labeled leukocytes
  • SPECT/CT hybrid camera

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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