Tc-99m HMPAO-labeled leukocyte scintigraphy with hybrid SPECT/CT detects perianal fistulas in Crohn disease

Luca Filippi; Livia Biancone; Carmelina Petruzziello; Orazio Schillaci

doi:10.1097/01.rlu.0000233082.89996.3a

Tc-99m HMPAO-labeled leukocyte scintigraphy with hybrid SPECT/CT detects perianal fistulas in Crohn disease

Luca Filippi, Livia Biancone, Carmelina Petruzziello, Orazio Schillaci

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Abstract

Scintigraphy with Tc-99m HMPAO-labeled leukocytes proved useful to diagnose intestinal lesions in Crohn disease (CD). The hybrid device combining single photon emission tomography (SPECT) and computed tomography (CT) has been reported to improve SPECT diagnostic accuracy matching functional and anatomic information. The authors describe a 30-year-old man with ileorectal anastomosis for CD. In this case, SPECT shows an area of leukocyte accumulation within the pelvis, and SPECT/CT precisely localizes this uptake along a perianal fistulous tract. This image indicates the usefulness of the hybrid SPECT/CT device to assess the site and the extent of CD lesions within the pelvic floor.

Original language	English
Pages (from-to)	541-542
Number of pages	2
Journal	Clinical Nuclear Medicine
Volume	31
Issue number	9
DOIs	https://doi.org/10.1097/01.rlu.0000233082.89996.3a
Publication status	Published - Sep 2006

Keywords

Crohn disease
Labeled leukocytes
SPECT/CT hybrid camera

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Radiological and Ultrasound Technology

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10.1097/01.rlu.0000233082.89996.3a

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title = "Tc-99m HMPAO-labeled leukocyte scintigraphy with hybrid SPECT/CT detects perianal fistulas in Crohn disease",

abstract = "Scintigraphy with Tc-99m HMPAO-labeled leukocytes proved useful to diagnose intestinal lesions in Crohn disease (CD). The hybrid device combining single photon emission tomography (SPECT) and computed tomography (CT) has been reported to improve SPECT diagnostic accuracy matching functional and anatomic information. The authors describe a 30-year-old man with ileorectal anastomosis for CD. In this case, SPECT shows an area of leukocyte accumulation within the pelvis, and SPECT/CT precisely localizes this uptake along a perianal fistulous tract. This image indicates the usefulness of the hybrid SPECT/CT device to assess the site and the extent of CD lesions within the pelvic floor.",

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AU - Filippi, Luca

AU - Biancone, Livia

AU - Petruzziello, Carmelina

AU - Schillaci, Orazio

PY - 2006/9

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AB - Scintigraphy with Tc-99m HMPAO-labeled leukocytes proved useful to diagnose intestinal lesions in Crohn disease (CD). The hybrid device combining single photon emission tomography (SPECT) and computed tomography (CT) has been reported to improve SPECT diagnostic accuracy matching functional and anatomic information. The authors describe a 30-year-old man with ileorectal anastomosis for CD. In this case, SPECT shows an area of leukocyte accumulation within the pelvis, and SPECT/CT precisely localizes this uptake along a perianal fistulous tract. This image indicates the usefulness of the hybrid SPECT/CT device to assess the site and the extent of CD lesions within the pelvic floor.

KW - Crohn disease

KW - Labeled leukocytes

KW - SPECT/CT hybrid camera

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Tc-99m HMPAO-labeled leukocyte scintigraphy with hybrid SPECT/CT detects perianal fistulas in Crohn disease

Abstract

Keywords

ASJC Scopus subject areas

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