Scintigrafia mammaria con 99mTc-SESTAMIBI, come supporto alle metodiche radiologiche nello studio delle lesioni mammarie

Translated title of the contribution: Technetium 99m Sestamibi scintigraphy as a support to radiologic imaging in the study of breast lesions

Rossella Occhiato, Orazio Schillaci, Laura Broglia, Roberta Danieli, Piero Narilli, Paolo Pavone, Francesco Scopinaro, Roberto Passariello

Research output: Contribution to journalArticlepeer-review

Abstract

Our study was aimed at investigating the efficacy of scintigraphy with 99mTc-Sestamibi (MIBI) as a support to mammography and US in the diagnosis and staging of breast cancer. Twenty-seven women with breast lesions were examined: the masses, detected at mammography and US, ranged in diameter 0.7 to 2.5 cm; mass features suggested a benign lesion in 5 patients, a malignant lesion in 9 patients and a questionable diagnosis in 13 patients. 99mTc-MIBI scintigraphic images were analyzed blind by two observers and the pattern was considered positive when tracer uptake was demonstrated at the lesion. In neoplastic lesions, tracer uptake was looked for also in the axilla. All the patients were submitted to surgery and, in case of malignancy, lymphadenectomy was also performed. MIBI scintigraphy was negative in 14/16 benign lesions and positive in 9/11 malignant lesions. Tracer uptake in the axilla was observed in 3 of 5 patients with nodal involvement. Scintigraphy had 82% sensitivity, 87% specificity and 85% accuracy in the diagnosis of breast cancers.

Translated title of the contributionTechnetium 99m Sestamibi scintigraphy as a support to radiologic imaging in the study of breast lesions
Original languageItalian
Pages (from-to)581-584
Number of pages4
JournalRadiologia Medica
Volume91
Issue number5
Publication statusPublished - May 1996

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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