Technical feasibility of real-time elastography to assess the peri-oral region in patients affected by systemic sclerosis

Paola Maria Cannaò, Valeriano Vinci, Fabio Caviggioli, Marco Klinger, Davide Orlandi, Francesco Sardanelli, Giovanni Serafini, Luca Maria Sconfienza

Research output: Contribution to journalArticlepeer-review

Abstract

Results: RTE demonstrated that the skin of the peri-oral region of patients affected by SSc was stiffer than that of controls, both overall (6;4–6 [median; 25–75th percentile] vs. 11;9–11, p 

Conclusion: RTE is a feasible modality to assess peri-oral region skin stiffness with excellent interobserver reproducibility. Further studies on a larger cohort of patients including more clinical data and measures are warranted to confirm our initial results.

Purpose: To evaluate the technical feasibility of real-time elastography (RTE) to assess the stiffness of the skin of the peri-oral region in patients affected by systemic sclerosis (SSc).

Methods: Six female patients affected by SSc (median age = 52 years) presenting with microstomia and six healthy controls matched for age and sex underwent RTE evaluation of the peri-oral region. Two operators with different experience evaluated the stiffness of the peri-oral region placing the probe in four different positions: parasagittal left (PL), parasagittal right (PR), upper axial (UA), lower axial (LA). Color map was converted into a semi-quantitative scale in which blue = 1, green = 2 and red = 3. Thus, each subject had a variable score ranging from 4 (four positions × value = 1) and 12 (four positions × value = 3). Mann–Whitney U and k statistics were used.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalClinical and Translational Imaging
Volume17
Issue number4
DOIs
Publication statusPublished - Oct 26 2014

Keywords

  • Microstomia
  • Real-time elastography
  • Skin
  • Systemic sclerosis
  • Ultrasonography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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