Technical Note: Multicenter study of TrueBeam FFF beams with a new stereotactic diode: Can a common small field signal ratio curve be defined?

Elisabetta Cagni, Serenella Russo, Giacomo Reggiori, Sara Bresciani, David Fedele, Mauro Iori, Carmelo Marino, Barbara Nardiello, Ruggero Ruggieri, Lidia Strigari, Pietro Mancosu

Research output: Contribution to journalArticle

Abstract

Purpose: Small radiation felds (<30 mm) are typically involved in stereotactic body radiation therapy procedures. Output factor measurements are subjected to large uncertainties. The signal ratio (SR) readings, defned as the ratio of central axis reading, respectively, in the actual feld size and in the reference feld size, were evaluated in several centers and a common mathematical description of the SR curve was investigated. Methods: A couple of new unshielded stereotactic diodes (Razor, IBA) was tested under eight di?erent TrueBeams using 10 MV ?attering flter free beams with high dose rate (2400 MU/min). Small felds, ranging from 6 to 50 mm, were analyzed in terms of profles and central axis point measurements. SRs were normalized to 30 mm feld and were calculated as a function of nominal feld size (NFS) and effective feld size (EFS). From SRs acquired using Razor1 (four centers), a theoretical equation was extrapolated. Three centers with Razor2 were used to test the mathematical relationship. Finally, the two diodes were directly compared in the last center. Results: The EFS was systematically smaller than NFS (p < 0.01) for all feld size ranges, with mean difference of 0.9±0.5 mm. The SR fts using the NFS and EFS had, respectively, R2 = 0.989 and R2 0.999. The Razor2 centers' mean deviation from the predicted SRs, using the NFS and EFS fts, was, respectively, 3.4% and 0.5%. The maximum deviations were 5.0% (6 mm feld size) for NFS and 1.9% for EFS. Maximum deviation of 0.5% between the two Razors was observed. Conclusions: EFS measurements were confrmed to be mandatory when comparing SRs over different centers. An equation establishing a functional relation between SRs and the EFS was obtained and tested for the new Razor diode.

Original languageEnglish
Pages (from-to)5570-5576
Number of pages7
JournalMedical Physics
Volume43
Issue number10
DOIs
Publication statusPublished - Oct 1 2016

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Multicenter Studies
Reading
Uncertainty
Radiotherapy
Radiation

Keywords

  • flattening filter free beam
  • multicenter study
  • radiotherapy
  • silicon diode detector
  • small field dosimetry
  • TrueBeam

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Technical Note : Multicenter study of TrueBeam FFF beams with a new stereotactic diode: Can a common small field signal ratio curve be defined? / Cagni, Elisabetta; Russo, Serenella; Reggiori, Giacomo; Bresciani, Sara; Fedele, David; Iori, Mauro; Marino, Carmelo; Nardiello, Barbara; Ruggieri, Ruggero; Strigari, Lidia; Mancosu, Pietro.

In: Medical Physics, Vol. 43, No. 10, 01.10.2016, p. 5570-5576.

Research output: Contribution to journalArticle

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abstract = "Purpose: Small radiation felds (<30 mm) are typically involved in stereotactic body radiation therapy procedures. Output factor measurements are subjected to large uncertainties. The signal ratio (SR) readings, defned as the ratio of central axis reading, respectively, in the actual feld size and in the reference feld size, were evaluated in several centers and a common mathematical description of the SR curve was investigated. Methods: A couple of new unshielded stereotactic diodes (Razor, IBA) was tested under eight di?erent TrueBeams using 10 MV ?attering flter free beams with high dose rate (2400 MU/min). Small felds, ranging from 6 to 50 mm, were analyzed in terms of profles and central axis point measurements. SRs were normalized to 30 mm feld and were calculated as a function of nominal feld size (NFS) and effective feld size (EFS). From SRs acquired using Razor1 (four centers), a theoretical equation was extrapolated. Three centers with Razor2 were used to test the mathematical relationship. Finally, the two diodes were directly compared in the last center. Results: The EFS was systematically smaller than NFS (p < 0.01) for all feld size ranges, with mean difference of 0.9±0.5 mm. The SR fts using the NFS and EFS had, respectively, R2 = 0.989 and R2 0.999. The Razor2 centers' mean deviation from the predicted SRs, using the NFS and EFS fts, was, respectively, 3.4{\%} and 0.5{\%}. The maximum deviations were 5.0{\%} (6 mm feld size) for NFS and 1.9{\%} for EFS. Maximum deviation of 0.5{\%} between the two Razors was observed. Conclusions: EFS measurements were confrmed to be mandatory when comparing SRs over different centers. An equation establishing a functional relation between SRs and the EFS was obtained and tested for the new Razor diode.",
keywords = "flattening filter free beam, multicenter study, radiotherapy, silicon diode detector, small field dosimetry, TrueBeam",
author = "Elisabetta Cagni and Serenella Russo and Giacomo Reggiori and Sara Bresciani and David Fedele and Mauro Iori and Carmelo Marino and Barbara Nardiello and Ruggero Ruggieri and Lidia Strigari and Pietro Mancosu",
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AU - Cagni, Elisabetta

AU - Russo, Serenella

AU - Reggiori, Giacomo

AU - Bresciani, Sara

AU - Fedele, David

AU - Iori, Mauro

AU - Marino, Carmelo

AU - Nardiello, Barbara

AU - Ruggieri, Ruggero

AU - Strigari, Lidia

AU - Mancosu, Pietro

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KW - silicon diode detector

KW - small field dosimetry

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