Telemedicine for screening diabetic retinopathy: The NO BLIND Italian multicenter study

NO BLIND Study Group

Research output: Contribution to journalArticle

Abstract

AIMS: Diabetic retinopathy (DR) represents the main cause of blindness among adults in the industrialized Countries. Use of telemedicine could offer an easy, smart specialist fundus oculi examination, as well as putting in a screening programme many patients who otherwise would be excluded.

MATERIALS AND METHODS: The NO BLIND is a transversal, multicentre, observational study. Its pilot phase involved nine public outpatient clinics for 6 months. As endpoint of the study, we assessed the prevalence of DR by retinography in a subset of the Italian population. Patients' fundus oculi photos were performed by trained diabetologists through a digital smart ophthalmoscope.

RESULTS: According to our endpoint, in the final study population (n = 1461), obtained excluding patients for whom retinography was not able to provide any diagnosis, DR prevalence was equal to 15.5%. According to the receiver operating characteristic (ROC) curve performed, we can observe how retinography appears a highly accurate method to detect DR (AUROC 0.971, 95% confidence interval, 0.954-0.989), with a specificity of the 100% and a sensitivity of the 94.3%.

CONCLUSIONS: Our findings, in an Italian setting, confirm main data in the literature about DR prevalence. Hence, telemedicine could represent an accurate, fast, and cheap method for screening of DR.

Original languageEnglish
Pages (from-to)e3113
JournalDiabetes/Metabolism Research and Reviews
DOIs
Publication statusE-pub ahead of print - Dec 13 2018

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Telemedicine
Diabetic Retinopathy
Multicenter Studies
Fundus Oculi
Ophthalmoscopes
Blindness
Ambulatory Care Facilities
Developed Countries
ROC Curve
Population
Observational Studies
Cross-Sectional Studies
Confidence Intervals

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Telemedicine for screening diabetic retinopathy : The NO BLIND Italian multicenter study. / NO BLIND Study Group.

In: Diabetes/Metabolism Research and Reviews, 13.12.2018, p. e3113.

Research output: Contribution to journalArticle

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title = "Telemedicine for screening diabetic retinopathy: The NO BLIND Italian multicenter study",
abstract = "AIMS: Diabetic retinopathy (DR) represents the main cause of blindness among adults in the industrialized Countries. Use of telemedicine could offer an easy, smart specialist fundus oculi examination, as well as putting in a screening programme many patients who otherwise would be excluded.MATERIALS AND METHODS: The NO BLIND is a transversal, multicentre, observational study. Its pilot phase involved nine public outpatient clinics for 6 months. As endpoint of the study, we assessed the prevalence of DR by retinography in a subset of the Italian population. Patients' fundus oculi photos were performed by trained diabetologists through a digital smart ophthalmoscope.RESULTS: According to our endpoint, in the final study population (n = 1461), obtained excluding patients for whom retinography was not able to provide any diagnosis, DR prevalence was equal to 15.5{\%}. According to the receiver operating characteristic (ROC) curve performed, we can observe how retinography appears a highly accurate method to detect DR (AUROC 0.971, 95{\%} confidence interval, 0.954-0.989), with a specificity of the 100{\%} and a sensitivity of the 94.3{\%}.CONCLUSIONS: Our findings, in an Italian setting, confirm main data in the literature about DR prevalence. Hence, telemedicine could represent an accurate, fast, and cheap method for screening of DR.",
author = "{NO BLIND Study Group} and Sasso, {Ferdinando Carlo} and Pafundi, {Pia Clara} and Aldo Gelso and Valeria Bono and Ciro Costagliola and Raffaele Marfella and Celestino Sardu and Luca Rinaldi and Raffaele Galiero and Carlo Acierno and {de Sio}, Chiara and Adinolfi, {Luigi Elio}",
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T2 - The NO BLIND Italian multicenter study

AU - NO BLIND Study Group

AU - Sasso, Ferdinando Carlo

AU - Pafundi, Pia Clara

AU - Gelso, Aldo

AU - Bono, Valeria

AU - Costagliola, Ciro

AU - Marfella, Raffaele

AU - Sardu, Celestino

AU - Rinaldi, Luca

AU - Galiero, Raffaele

AU - Acierno, Carlo

AU - de Sio, Chiara

AU - Adinolfi, Luigi Elio

N1 - © 2018 John Wiley & Sons, Ltd.

PY - 2018/12/13

Y1 - 2018/12/13

N2 - AIMS: Diabetic retinopathy (DR) represents the main cause of blindness among adults in the industrialized Countries. Use of telemedicine could offer an easy, smart specialist fundus oculi examination, as well as putting in a screening programme many patients who otherwise would be excluded.MATERIALS AND METHODS: The NO BLIND is a transversal, multicentre, observational study. Its pilot phase involved nine public outpatient clinics for 6 months. As endpoint of the study, we assessed the prevalence of DR by retinography in a subset of the Italian population. Patients' fundus oculi photos were performed by trained diabetologists through a digital smart ophthalmoscope.RESULTS: According to our endpoint, in the final study population (n = 1461), obtained excluding patients for whom retinography was not able to provide any diagnosis, DR prevalence was equal to 15.5%. According to the receiver operating characteristic (ROC) curve performed, we can observe how retinography appears a highly accurate method to detect DR (AUROC 0.971, 95% confidence interval, 0.954-0.989), with a specificity of the 100% and a sensitivity of the 94.3%.CONCLUSIONS: Our findings, in an Italian setting, confirm main data in the literature about DR prevalence. Hence, telemedicine could represent an accurate, fast, and cheap method for screening of DR.

AB - AIMS: Diabetic retinopathy (DR) represents the main cause of blindness among adults in the industrialized Countries. Use of telemedicine could offer an easy, smart specialist fundus oculi examination, as well as putting in a screening programme many patients who otherwise would be excluded.MATERIALS AND METHODS: The NO BLIND is a transversal, multicentre, observational study. Its pilot phase involved nine public outpatient clinics for 6 months. As endpoint of the study, we assessed the prevalence of DR by retinography in a subset of the Italian population. Patients' fundus oculi photos were performed by trained diabetologists through a digital smart ophthalmoscope.RESULTS: According to our endpoint, in the final study population (n = 1461), obtained excluding patients for whom retinography was not able to provide any diagnosis, DR prevalence was equal to 15.5%. According to the receiver operating characteristic (ROC) curve performed, we can observe how retinography appears a highly accurate method to detect DR (AUROC 0.971, 95% confidence interval, 0.954-0.989), with a specificity of the 100% and a sensitivity of the 94.3%.CONCLUSIONS: Our findings, in an Italian setting, confirm main data in the literature about DR prevalence. Hence, telemedicine could represent an accurate, fast, and cheap method for screening of DR.

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DO - 10.1002/dmrr.3113

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