Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis

Enrico Franceschi; Giovanna Cavallo; Luciano Scopece; Roberta Degli Esposti; Gabriele Paioli; Anna Paioli; Emanuela Palmerini; Maria Pia Foschini; Anna Federica Marliani; Lucio Crinò

doi:10.1007/s11060-004-5672-5

Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis

Enrico Franceschi, Giovanna Cavallo, Luciano Scopece, Roberta Degli Esposti, Gabriele Paioli, Anna Paioli, Emanuela Palmerini, Maria Pia Foschini, Anna Federica Marliani, Lucio Crinò

Research output: Contribution to journal › Article › peer-review

Abstract

Herein we describe the case of a patient with primary diffuse leptomeningeal gliomatosis (PDLG). After surgery and ventriculoperitoneal shunt placement, due to poor general conditions, the patient was not eligible for radiotherapy. For this reason we decided to start a systemic chemotherapy treatment with Temozolomide (150 mg/m² per day for 5 days every 4 weeks). After three cycles a partial response was achieved with a clear improvement of general conditions. In our knowledge, this is the first time that PDLG treatment with Temozolomide has been described.

Original language	English
Pages (from-to)	261-264
Number of pages	4
Journal	Journal of Neuro-Oncology
Volume	73
Issue number	3
DOIs	https://doi.org/10.1007/s11060-004-5672-5
Publication status	Published - Jul 2005

Keywords

Chemotherapy
Primary diffuse leptomeningeal gliomatosis
Temozolomide

ASJC Scopus subject areas

Clinical Neurology
Cancer Research
Oncology
Neuroscience(all)

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Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis. / Franceschi, Enrico; Cavallo, Giovanna; Scopece, Luciano; Degli Esposti, Roberta; Paioli, Gabriele; Paioli, Anna; Palmerini, Emanuela; Foschini, Maria Pia; Marliani, Anna Federica; Crinò, Lucio.

In: Journal of Neuro-Oncology, Vol. 73, No. 3, 07.2005, p. 261-264.

Research output: Contribution to journal › Article › peer-review

Franceschi, Enrico ; Cavallo, Giovanna ; Scopece, Luciano ; Degli Esposti, Roberta ; Paioli, Gabriele ; Paioli, Anna ; Palmerini, Emanuela ; Foschini, Maria Pia ; Marliani, Anna Federica ; Crinò, Lucio. / Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis. In: Journal of Neuro-Oncology. 2005 ; Vol. 73, No. 3. pp. 261-264.

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AU - Paioli, Gabriele

AU - Paioli, Anna

AU - Palmerini, Emanuela

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