Temporal change in the use of genotypic resistance testing over the years 1999-2003

M. Santoro, F. Ceccherini-Silberstein, C. Gori, V. Svicher, F. Forbici, M. C. Bellocchi, R. D'Arrigo, A. Bertoli, S. Giannella, M. P. Trotta, S. Bonfigli, A. Antinori, C. F. Perno

Research output: Contribution to journalArticlepeer-review


The evaluation of resistance test perception by clinicians over the years 1999-2003 was assessed in an Italian cohort. The results on 2233 samples from 1416 HIV-1 infected patients show an increase in HIV-1 drug resistance test requests over time, with a plateau reached in the last three years. CD4-cell count at the time of genotype request progressively increased. In particular, the median CD4 cell count of drug-treated patients increased from 221×106 cells/l [interquartile range (IQR): 109-368] in 1999 to 296×106 cells/l (IQR: 166-478) in 2003 (p

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalNew Microbiologica
Issue number2 SUPPL. 1
Publication statusPublished - 2004


  • AIDS
  • Disease progression
  • Drug-resistance
  • Genotyping test
  • HIV-1

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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