Temporal lobe electroencephalogram power modifications during olfactory stimulation in HIV-infected patients

Barbara Grassi, Marco Locatelli, Adriano Lazzarin, Silvio Scarone

Research output: Contribution to journalArticlepeer-review

Abstract

Evidence derived from studies concerning brain metabolism and brain electrical activity suggests that temporal lobe functioning is impaired in the course of HIV infection. To test the hypothesis of temporal lobe dysfunction in HIV infection, we utilized computerized electroencephalogram (EEG) analysis to evaluate temporal lobe EEG power modifications induced by olfactory stimulation in 10 HIV-infected patients as compared with 10 seronegative control subjects. Our findings show that HIV-infected patients respond to olfactory stimulation with an increase in temporal lobe slow electrical activity (theta EEG power), whereas control subjects show a decrease in the same activity. The theta EEG power increase during olfactory stimulation in HIV-infected patients can be interpreted as a paradoxical response of the deep temporal regions to specific procedures, supporting the hypothesis of temporal lobe dysfunction in HIV infection.

Original languageEnglish
Pages (from-to)547-551
Number of pages5
JournalAIDS Research and Human Retroviruses
Volume12
Issue number6
Publication statusPublished - Apr 10 1996

ASJC Scopus subject areas

  • Immunology
  • Virology

Fingerprint Dive into the research topics of 'Temporal lobe electroencephalogram power modifications during olfactory stimulation in HIV-infected patients'. Together they form a unique fingerprint.

Cite this