Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia

P Capogrosso, U Capitanio, EA Vertosick, E Ventimiglia, F Chierigo, D Oreggia, D Moretti, A Briganti, AJ Vickers, F Montorsi, A Salonia

Research output: Contribution to journalArticle

Abstract

Objective: To assess changes in the rate of incidental prostate cancer (PCa) after benign prostatic hyperplasia (BPH) surgery over the last decade. Materials and Methods: We identified 1177 patients surgically treated for BPH (open prostatectomy, transurethral resection or holmium laser enucleation [HoLEP] of the prostate) in 2007-2016 at a single European academic center. Local polynomial regression was used to explore changes in the rate of incidental PCa detected after BPH surgery and of preoperative biopsy performed over time. Logistic regression analyses tested the association of incidental PCa diagnosis with year of surgery and preoperative biopsy. Results: Incidental PCa was found in 6.4% (74) of cases, 67 (91%) with Grade group 1 disease. We observed an increased incidence of PCa diagnosis after BPH surgery over time (odds ratio [OR]: 1.12; 95%confidence interval [CI]: 1.02-1.24, P =.02) along with a concomitant decrease in the rate of preoperative prostate biopsies (OR: 0.83; 95%CI: 0.79-0.88, P
Original languageEnglish
Pages (from-to)152-157
Number of pages6
JournalUrology
Volume122
DOIs
Publication statusPublished - 2018

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Prostatic Hyperplasia
Prostatic Neoplasms
Biopsy
Prostate
Odds Ratio
Confidence Intervals
Transurethral Resection of Prostate
Solid-State Lasers
Logistic Models
Regression Analysis
Incidence

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Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia. / Capogrosso, P; Capitanio, U; Vertosick, EA; Ventimiglia, E; Chierigo, F; Oreggia, D; Moretti, D; Briganti, A; Vickers, AJ; Montorsi, F; Salonia, A.

In: Urology, Vol. 122, 2018, p. 152-157.

Research output: Contribution to journalArticle

Capogrosso, P ; Capitanio, U ; Vertosick, EA ; Ventimiglia, E ; Chierigo, F ; Oreggia, D ; Moretti, D ; Briganti, A ; Vickers, AJ ; Montorsi, F ; Salonia, A. / Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia. In: Urology. 2018 ; Vol. 122. pp. 152-157.
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abstract = "Objective: To assess changes in the rate of incidental prostate cancer (PCa) after benign prostatic hyperplasia (BPH) surgery over the last decade. Materials and Methods: We identified 1177 patients surgically treated for BPH (open prostatectomy, transurethral resection or holmium laser enucleation [HoLEP] of the prostate) in 2007-2016 at a single European academic center. Local polynomial regression was used to explore changes in the rate of incidental PCa detected after BPH surgery and of preoperative biopsy performed over time. Logistic regression analyses tested the association of incidental PCa diagnosis with year of surgery and preoperative biopsy. Results: Incidental PCa was found in 6.4{\%} (74) of cases, 67 (91{\%}) with Grade group 1 disease. We observed an increased incidence of PCa diagnosis after BPH surgery over time (odds ratio [OR]: 1.12; 95{\%}confidence interval [CI]: 1.02-1.24, P =.02) along with a concomitant decrease in the rate of preoperative prostate biopsies (OR: 0.83; 95{\%}CI: 0.79-0.88, P",
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T1 - Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia

AU - Capogrosso, P

AU - Capitanio, U

AU - Vertosick, EA

AU - Ventimiglia, E

AU - Chierigo, F

AU - Oreggia, D

AU - Moretti, D

AU - Briganti, A

AU - Vickers, AJ

AU - Montorsi, F

AU - Salonia, A

PY - 2018

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N2 - Objective: To assess changes in the rate of incidental prostate cancer (PCa) after benign prostatic hyperplasia (BPH) surgery over the last decade. Materials and Methods: We identified 1177 patients surgically treated for BPH (open prostatectomy, transurethral resection or holmium laser enucleation [HoLEP] of the prostate) in 2007-2016 at a single European academic center. Local polynomial regression was used to explore changes in the rate of incidental PCa detected after BPH surgery and of preoperative biopsy performed over time. Logistic regression analyses tested the association of incidental PCa diagnosis with year of surgery and preoperative biopsy. Results: Incidental PCa was found in 6.4% (74) of cases, 67 (91%) with Grade group 1 disease. We observed an increased incidence of PCa diagnosis after BPH surgery over time (odds ratio [OR]: 1.12; 95%confidence interval [CI]: 1.02-1.24, P =.02) along with a concomitant decrease in the rate of preoperative prostate biopsies (OR: 0.83; 95%CI: 0.79-0.88, P

AB - Objective: To assess changes in the rate of incidental prostate cancer (PCa) after benign prostatic hyperplasia (BPH) surgery over the last decade. Materials and Methods: We identified 1177 patients surgically treated for BPH (open prostatectomy, transurethral resection or holmium laser enucleation [HoLEP] of the prostate) in 2007-2016 at a single European academic center. Local polynomial regression was used to explore changes in the rate of incidental PCa detected after BPH surgery and of preoperative biopsy performed over time. Logistic regression analyses tested the association of incidental PCa diagnosis with year of surgery and preoperative biopsy. Results: Incidental PCa was found in 6.4% (74) of cases, 67 (91%) with Grade group 1 disease. We observed an increased incidence of PCa diagnosis after BPH surgery over time (odds ratio [OR]: 1.12; 95%confidence interval [CI]: 1.02-1.24, P =.02) along with a concomitant decrease in the rate of preoperative prostate biopsies (OR: 0.83; 95%CI: 0.79-0.88, P

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SN - 0090-4295

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