Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 152-157 |
| Number of pages | 6 |
| Journal | Urology |
| Volume | 122 |
| DOIs | |
| Publication status | Published - 2018 |
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Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia. / Capogrosso, P; Capitanio, U; Vertosick, EA; Ventimiglia, E; Chierigo, F; Oreggia, D; Moretti, D; Briganti, A; Vickers, AJ; Montorsi, F; Salonia, A.
In: Urology, Vol. 122, 2018, p. 152-157.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia
AU - Capogrosso, P
AU - Capitanio, U
AU - Vertosick, EA
AU - Ventimiglia, E
AU - Chierigo, F
AU - Oreggia, D
AU - Moretti, D
AU - Briganti, A
AU - Vickers, AJ
AU - Montorsi, F
AU - Salonia, A
PY - 2018
Y1 - 2018
N2 - Objective: To assess changes in the rate of incidental prostate cancer (PCa) after benign prostatic hyperplasia (BPH) surgery over the last decade. Materials and Methods: We identified 1177 patients surgically treated for BPH (open prostatectomy, transurethral resection or holmium laser enucleation [HoLEP] of the prostate) in 2007-2016 at a single European academic center. Local polynomial regression was used to explore changes in the rate of incidental PCa detected after BPH surgery and of preoperative biopsy performed over time. Logistic regression analyses tested the association of incidental PCa diagnosis with year of surgery and preoperative biopsy. Results: Incidental PCa was found in 6.4% (74) of cases, 67 (91%) with Grade group 1 disease. We observed an increased incidence of PCa diagnosis after BPH surgery over time (odds ratio [OR]: 1.12; 95%confidence interval [CI]: 1.02-1.24, P =.02) along with a concomitant decrease in the rate of preoperative prostate biopsies (OR: 0.83; 95%CI: 0.79-0.88, P
AB - Objective: To assess changes in the rate of incidental prostate cancer (PCa) after benign prostatic hyperplasia (BPH) surgery over the last decade. Materials and Methods: We identified 1177 patients surgically treated for BPH (open prostatectomy, transurethral resection or holmium laser enucleation [HoLEP] of the prostate) in 2007-2016 at a single European academic center. Local polynomial regression was used to explore changes in the rate of incidental PCa detected after BPH surgery and of preoperative biopsy performed over time. Logistic regression analyses tested the association of incidental PCa diagnosis with year of surgery and preoperative biopsy. Results: Incidental PCa was found in 6.4% (74) of cases, 67 (91%) with Grade group 1 disease. We observed an increased incidence of PCa diagnosis after BPH surgery over time (odds ratio [OR]: 1.12; 95%confidence interval [CI]: 1.02-1.24, P =.02) along with a concomitant decrease in the rate of preoperative prostate biopsies (OR: 0.83; 95%CI: 0.79-0.88, P
U2 - 10.1016/j.urology.2018.07.028
DO - 10.1016/j.urology.2018.07.028
M3 - Article
VL - 122
SP - 152
EP - 157
JO - Urology
JF - Urology
SN - 0090-4295
ER -