Temporal trends and determinants of peripartum hysterectomy in Lombardy, Northern Italy, 1996-2010

Fabio Parazzini, Elena Ricci, Sonia Cipriani, Francesca Chiaffarino, Renata Bortolus, Vito Chiantera, Giuseppe Bulfoni

Research output: Contribution to journalArticlepeer-review


Purpose: To analyze the temporal trends of peripartum hysterectomy (PH) in the period 1996-2010 in Lombardy, Italy. Methods: Using data from the Regional Database, PH ratios/1,000 deliveries were calculated from 1996 to 2010, in strata of age and mode of delivery among women resident in Lombardy, Italy. PH cases were identified searching the database for the ICD-9 and ICD-10 codes for subtotal and total hysterectomy. PH ratios/1,000 deliveries in strata of age, mode of delivery and calendar year were computed. Poisson's regression analysis was used to test trend over time. Results: A total of 905 PH and 1,289,163 deliveries were recorded between 1996 and 2010. The overall PH ratio was 0.70/1,000 deliveries. The PH ratio/1,000 deliveries increased over time, being 0.57 in 1996 and 0.88/1,000 deliveries in 2010 (P <0.0001). After including calendar year, mode of delivery and maternal age in the Poisson's regression equation, no significant linear trend emerged in the PH ratio over time (P = 0.28). Women who underwent cesarean section (CS) (CS vs. vaginal delivery: OR 5.66, 95 % CI 4.91-6.54) and older women were at increased risk of PH (maternal age ≥40 vs.

Original languageEnglish
Pages (from-to)223-228
Number of pages6
JournalArchives of Gynecology and Obstetrics
Issue number2
Publication statusPublished - Feb 2013


  • Cesarean section
  • Hysterectomy
  • Maternal age
  • Peripartum
  • Risk factor
  • Temporal trend

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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