Temporo-mesial extraventricular neurocytoma and cortical dysplasia in focal temporal lobe epilepsy

Marco Giulioni, Matteo Martinoni, Guido Rubboli, Gianluca Marucci, Anna Federica Marliani, Stella Battaglia, Filippo Badaloni, Eugenio Pozzati, Fabio Calbucci

Research output: Contribution to journalArticle

Abstract

We describe a 17-year-old boy with a left extraventricular temporo-mesial neurocytoma associated with cortical dysplasia causing focal pharmacoresistant temporal lobe epilepsy. He presented with a long history of medically refractory, temporal complex partial seizures. MRI showed a left temporo-mesial lesion suspect to be a low-grade tumor. Based on the pre-operative non-invasive neurophysiological studies, the patient underwent a left tailored temporal antero-mesial resection. Histopathological examination showed an extraventricular neurocytoma associated with architectural dysplasia (Type 1a) of the temporal pole. The patient was seizure-free at 2 years follow-up. Extraventricular neurocytomas must be considered in the differential diagnosis of the plethora of low-grade tumors associated with focal epilepsy that typically involve the temporal lobe, and are frequently associated with focal cortical dysplasia.

Original languageEnglish
Pages (from-to)147-148
Number of pages2
JournalJournal of Clinical Neuroscience
Volume18
Issue number1
DOIs
Publication statusPublished - Jan 2011

Keywords

  • Cortical dysplasias
  • Epilepsy surgery
  • Extraventricular neurocytoma
  • Glioneuronal tumors
  • Pharmacoresistant epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

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