Teniposide is not effective in chronic lymphocytic leukemia

V. Zagonel, U. Tirelli, A. Veronesi, E. Galligioni, S. Tumolo, M. Roncadin, A. Carbone, E. Grigoletto

Research output: Contribution to journalArticlepeer-review

Abstract

Teniposide has been evaluated in a phase II clinical trial in chronic lymphocytic leukemia (CLL). Among 16 consecutive patients with CLL entered in the study and treated with Teniposide, 100 mg/m2 weekly, no objective response was observed. Toxicity was generally mild and mainly hematologic. Teniposide at this dosage and schedule is an inactive drug in CLL.

Original languageEnglish
Pages (from-to)59-61
Number of pages3
JournalBlut
Volume52
Issue number1
DOIs
Publication statusPublished - Jan 1986

Keywords

  • Chronic lymphocytic leukemia
  • Teniposide
  • VM-26

ASJC Scopus subject areas

  • Hematology

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