We report the case of a 36 year-old man with relapsing undifferentiated nasopharyngealcarcinoma treated with a re-irradiation Cyberknife, who subsequently developed tensionpneumocephalus due to a cerebrospinal fluid leakage located at the clivus. The fistula wascaused by osteonecrosis of the skull base secondary to the tumor invasion and to the seque-lae of the radiotherapy. An endoscopic endonasal technique was used in order to repairthe defect, with a peduncolated nasoseptal flap harvested to perform the skull base recon-struction. In this paper, we discuss the importance of identifying this possible complicationrelated to radiotherapy in the management of neoplasm along the skull base; moreover, therole of endoscopy in the diagnosis and treatment of skull base fistulas is also described andcommented.
- Endoscopic endonasal approach
- Nasopharyngeal carcinoma (NPC)
- Skull-base fistula
- Tension pneumocephalus (TP)
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging