An original thermographic method to evaluate the vasoconstrictive activity of a new steroid, alclometasone dipropionate cream 0.1% is reported. Eighteen healthy patients (12 women and 6 men) were studied applying the same quantity of the cream and his placebo on symmetrical area of the upper back. In four of these, the applications were repeated twice a day for seven days. The results show that in the sides treated with alclometasone the vasoconstrictive time increases progressively with the number of the applications, from 4 hours after a single one to 18 hours after 14 applications. The authors emphasize the validity of thermography in evaluating corticosteroids vasoconstriction as well as in establishing the correct dosage in order to avoid side effects.
|Translated title of the contribution||Termographic evaluation of the vasoconstrictive activity of a topical corticosteroid|
|Number of pages||7|
|Issue number||1 SUPPL.|
|Publication status||Published - 1989|
ASJC Scopus subject areas