Abstract
Tumor-infiltrating lymphocytes influence colorectal cancer progression. We have recently documented that tertiary lymphoid tissue in the colorectal cancer microenvironment orchestrates lymphocyte infiltration and that tertiary lymphoid tissue and lymphocytes cooperate in a coordinated antitumor immune response to improve patient outcome. Thus, tertiary lymphoid tissue represents a potential target in the design of tailored immune-based therapeutic approaches.
Original language | English |
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Article number | e28850 |
Journal | OncoImmunology |
Volume | 3 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2014 |
Keywords
- Biomarkers
- Colorectal cancer
- Immunotherapy
- Prognosis
- Tertiary lymphoid tissue
- Tumor-infiltrating lymphocytes
ASJC Scopus subject areas
- Immunology and Allergy
- Oncology
- Immunology